Grand River Aseptic Manufacturing Installs Sterile Filling Lines

Grand River Aseptic Manufacturing (GRAM), an injectable contract development and manufacturing organization (CDMO), has completed Phase II of its facility expansion, which includes the installation of GRAM’s two new sterile Bausch+Ströbel filling lines. Now, with a total of three separate fill lines, GRAM’s filling capacity reaches over 50 million units per year, with space to serve a variety of pharma and biotech customers.

The CDMO’s state-of-the-art aseptic filling facility is designed with independent formulation and filling suites. Working closely with OEMs (original equipment manufacturers) on selecting the new equipment, GRAM installed a Bausch+Ströbel VarioSys modular vial and syringe/cartridge fill line with SKAN isolator. In addition, GRAM installed a second Bausch+Ströbel high-speed vial fill line with SKAN isolator, identical in technology to the previously installed fill line with IMA lyophilizer, which began manufacturing product in September 2020.

“ ... Continuity of technology across all our fill lines benefits our clients, as their products transition from the clinic to the market," says Tom Ross, president and CEO. "The capabilities established at GRAM—with new facilities and equipment—will better serve our clients focused on high-value biologic drug products.”