
Episode 4 of Supply Chain Signal examines PhRMA’s legal challenge to CMS ’ GLOBE model and whether manufacturers can lower costs, expand U.S. production and strengthen supply chain resilience all at once.
Tasked with the delivery of two ultra-sensitive gene therapies to Japan – treatments targeting vision loss that required continuous -80°C temperature control and dry ice replenishment throughout an 80-hour transit – Marken activated a customized, precision-driven supply chain strategy. Navigating one of the world’s most complex regulatory landscapes for advanced therapies, success depended on flawless execution, specialized handling protocols, and seamless cross-functional collaboration. So how did Marken overcome these high-stakes challenges – ensuring the integrity of these transformative therapeutics while exceeding client expectations? Read the full case study to find out.






