Pharma Pulse: Novartis Expands Cardiovascular Pipeline, Flu Severity Drivers Identified in Seniors, and Fixing Medication Nonadherence

Welcome to Pharma Pulse, a Pharmaceutical Commerce podcast where we bring you the latest insights shaping patient access, supply chain/logistics, data & tech, and healthcare innovation. I’m your host, and today we’re covering a major cardiovascular acquisition by Novartis, new research into flu severity in older adults, and practical solutions for improving medication adherence.

• Novartis has announced plans to acquire Tourmaline Bio in a deal that strengthens its cardiovascular pipeline. The acquisition centers on Pacibekitug, an experimental therapy for cardiovascular disease that could address significant unmet need. Analysts say the move reinforces Novartis’ strategy to expand in cardiometabolic diseases, an area of growing focus for both innovation and competition.
• In other news, a new study has identified key biological and immunological factors that make influenza infections more severe in older adults. Researchers point to age-related changes in immune response and chronic inflammation as major contributors. The findings could inform the development of more effective flu vaccines and targeted therapies, especially as older adults remain at highest risk of hospitalization and death during flu season.
• Lastly, a recent report highlights five common reasons patients don’t take their medications—including cost, side effects, complexity of regimens, lack of perceived need, and simple forgetfulness. Experts recommend solutions ranging from improved patient education and simplified dosing to digital reminders and better affordability options. Addressing nonadherence remains critical, as it is estimated to contribute to thousands of preventable hospitalizations and billions in excess healthcare costs each year.

From pipeline growth in cardiovascular disease to insights into flu biology and practical strategies for boosting adherence, these stories highlight the blend of science and patient care shaping today’s pharma landscape.

That’s it for this episode of Pharma Pulse. For more insights on trends transforming pharmaceutical access and care delivery, visit pharmaceuticalcommerce.com.

Thanks for listening—until next time, stay well and stay informed.

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