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Pharma Pulse 8/6/25: GT-02287 Shows Promise in Parkinson's Patients with and Without GBA1 Mutation; How Remote Monitoring Enhances Trial Efficiency and Patient Safety

Key Takeaways

  • GT-02287 shows promise in Parkinson's patients with and without GBA1 mutation, with a Phase II trial planned for 2026.
  • Remote monitoring improves trial efficiency and patient safety by enabling real-time data access and reducing site burden.
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GT-02287 Shows Promise in Parkinson's Patients with and Without GBA1 Mutation

In an interview with Pharmaceutical Executive, GAIN Therapeutics CEO Gene Mack shared that GT-02287, originally developed for Parkinson’s patients with the GBA1 mutation, is showing early promise in both mutated and idiopathic cases, with a pivotal Phase II trial planned for early 2026 following ahead-of-schedule enrollment in the ongoing Phase Ib study.

How Remote Monitoring Enhances Trial Efficiency and Patient Safety

In an interview with Applied Clinical Trials, Luke Wilson, senior director of biotech and pharma services at Thermo Fisher Scientific, emphasized that remote monitoring improves clinical trial efficiency and patient safety by enabling real-time data access, reducing site burden, and supporting faster, more informed decision-making through integrated, technology-driven systems.

Flu Fighters: Pharmacists Partnering to Protect Communities

Michael Fleck, PharmD, a PGY-1 community-based pharmacy resident, outlines how community pharmacists can drive influenza vaccination uptake by partnering with local organizations, addressing barriers through tailored outreach, and making vaccines more visible, accessible, and trusted within the communities they serve.

Gift Launches $200M Initiative for the Weill Cancer Hub West

A $100 million matching grant from the Weill Family Foundation has launched the Weill Cancer Hub West, a $200 million collaboration between UCSF and Stanford that aims to transform cancer research and care over the next decade through pioneering projects in cellular therapies, AI-powered treatment strategies, precision nutrition, and personalized medicine.

Psyched Perspectives: Trauma, Transformations, and Truth

In the latest episode of Psyched Perspectives, psychiatrists Frank A. Clark, MD, and Emily Lafferman, MD, explore themes of trauma, transformation, and truth through poetry and personal reflection, highlighting how creative expression helps clinicians process their own experiences while deepening their connection with patients and each other.

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